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Intravenous tocilizumab: For vials: Store between 2°C - 8°C, do not freeze. Keep the container in the outer carton in order to protect from light.
For prepared infusion solution: The prepared infusion solution of tocilizumab is physically and chemically stable in 0.9% w/v sodium chloride solution at 30ºC for 24 hours.
From a microbiological point of view, the prepared infusion should be used immediately. If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and should not be longer than 24 hours at 2°C - 8°C, unless dilution has taken place in controlled and validated aseptic conditions.
Subcutaneous tocilizumab: Store the PFS in a refrigerator at a temperature of 2°C-8°C (36-46°F). Do not freeze, keep in carton to protect from light, and keep dry. Once removed from the refrigerator, the PFS can be stored up to 2 weeks at or below 30°C. The PFS must always be kept in the carton.
